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Assessment of absorbed dose distribution for the in vitro setup at the VITA facility
Petrunya D. S. 1,2, Azarkin M. Yu. 1, Zavestovskaya I. N. 1,2, Kasatov D. A. 3, Kirakosyan M. R. 1, Razdrogova Ya. V.1, Taskaev S. Yu. 1,3,4
1Lebedev Physical Institute, Russian Academy of Sciences, Moscow, Russia
2National Research Center “Kurchatov Institute”, Moscow, Russia
3 Budker Institute of Nuclear Physics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia
4Novosibirsk State University, Novosibirsk, Russia
Email: d.petrunya@lebedev.ru, azarkinmy@lebedev.ru, zavestovskayain@lebedev.ru, d.a.kasatov@inp.nsk.su, kirakosyanmr@lebedev.ru, razdrogovaya@gmail.com, s.yu.taskaev@inp.nsk.su

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In this study, the spatial distribution of an absorbed dose and its components were assessed for the in vitro setup of the VITA accelerator-based neutron source, operating at the Budker Institute of Nuclear Physics, Siberian Branch of the Russian Academy of Sciences. Namely, the total and boron doses were obtained for cryovials placed at different distances from the neutron field axis. The cryovials contained a cell suspension doped with the realistic concentration of 10B isotope. Additionally, the dependence of the quantities on the neutron moderator chemical composition and thickness was investigated. Keywords: boron neutron capture therapy, absorbed dose, in vitro setup, Monte Carlo simulation.
  1. M. Ahmed, D. Alberti, S. Altieri, T. Asano, I. Auterinen, R. Bedogni, O. Belyakov, C. Besnard-Vauterin, S. Bortolussi, B. Busser, J. Capala, Y.-W. Chen, F.-I. Chou, O. Ciraj-Bjelac, G. Cruikshanck (Collaboration), Advances in boron neutron capture therapy (International Atomic Energy Agency, Vienna, Austria, 2023)
  2. R.F. Barth, G. Wu, M.G.H. Vicente, J.C. Grecula, N. Gupta, Cancer Commun., 44 (8), 889 (2024). DOI: 10.1002/cac2.12581
  3. S.Yu. Taskaev, Uskoritel'nyi istochnik neitronov VITA (Fizmatlit, M., 2024) (in Russian)
  4. X. Cheng, F. Li, L. Liang, Curr. Oncol., 29 (10), 7868 (2022). DOI: 10.3390/curroncol29100622
  5. T. Togtokhtur, E.B. Dushanov, T.A. Kulahava, M. Batmunkh, A.N. Bugay, Phys. Part. Nucl. Lett., 21, 811 (2024). DOI: 10.1134/S1547477124701425
  6. M.Yu. Azarkin, I.N. Zavestovskaya, M.R. Kirakosyan, D.S. Petrunya, D.A. Kasatov, V.D. Konovalova, S.Yu. Taskaev, Bull. Lebedev Phys. Inst., 52 (2), 72 (2025). DOI: 10.3103/S1068335624602371
  7. T. Sycheva, E. Berendeev, G. Verkhovod, S. Taskaev, Appl. Radiat. Isot., 198, 110818 (2023). DOI: 10.1016/j.apradiso.2023.110818
  8. A.I. Kasatova, K.S. Kuzmina, D.A. Kasatov, E.V. Barmina, K.O. Aiyyzhy, P.A. Kotelnikova, M.S. Grigoryeva, D.S. Petrunya, E.L. Zavjalov, S.Yu. Taskaev, S.M. Deyev, I.N. Zavestovskaya, Bull. Lebedev Phys. Inst., 52 (2), 95 (2025). DOI: 10.3103/S1068335624602541
  9. I.N. Zavestovskaya, A.I. Kasatova, D.A. Kasatov, J.S. Babkova, I.V. Zelepukin, K.S. Kuzmina, G.V. Tikhonowski, A.I. Pastukhov, K.O. Aiyyzhy, E.V. Barmina, A.A. Popov, I.A. Razumov, E.L. Zavjalov, M.S. Grigoryeva, S.M. Klimentov, V.A. Ryabov, S.M. Deyev, S.Y. Taskaev, A.V. Kabashin, Int. J. Mol. Sci., 24 (23), 17088 (2023). DOI: 10.3390/ijms242317088
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