Shmidt N. M. 1, Usikov A. S.1,2, Vorobyev S. V.1,3,4, Plekhanov A. Yu.5, Ternovych I. K.3,4, Roenkov A. D.2, Puzyk M. V.6, Shabunina E. I.1, Gushchina E. V.1, Lebedev S. P.1, Lebedev A. A.1, Smirnov A. N.1, Priobrazhensky S. Yu.1, Tanklevskaya E. M.1
1Ioffe Institute, St. Petersburg, Russia
2Nitride Crystals Group, St. Petersburg, Russia
3Almazov National Medical Research Center, St. Petersburg, Russia
4St. Petersburg State Pediatric Medical University, St. Petersburg, Russia
5 Smorodintsev Research Institute of Influenza (a Russian Ministry of Health federal institution), St. Petersburg, Russia
6Herzen State Pedagogical University of Russia, St. Petersburg, Russia
Email: Natalia.Shmidt@mail.ioffe.ru
A comprehensive study of biosensors for β-amyloid and tau-protein marker detection based on graphene films obtained by thermal decomposition of semi-insulating SiC has shown the possibility of doubling the biosensor response without using graphene functionalization. It has been found that one of the reasons for the low reproducibility of detection results and the decrease in the biosensor response is the aggregation of antibodies and proteins in defective areas of graphene. Keywords: nanomaterials, graphene, biosensors, Alzheimer's disease.
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Дата начала обработки статистических данных - 27 января 2016 г.