Technical Physics
To authors
Electrical stimulation of human dermal fibroblasts on conducting matrix
Kolbe K. A.1,2, Shishov M. A.1,2, Sapurina I. Yu.2, Smirnova N. V.1,2, Kodolova-Chukhontseva V. V.1, Dresvyanina E. N.1, Kamalov A. M.1, Yudin V.E 1,2
1Peter the Great Saint-Petersburg Polytechnic University, St. Petersburg, Russia
2Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
2Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Email: nvsmirnoff@yandex.ru
Conducting composite based on biocompatible chitosan and single wall carbon nanotubes was used as a matrix for electrical stimulation of human fibroblasts. Parameters of ionic and electronic currents passing through the matrix upon applying cyclic potentials (±100 mV) were studied; the scaffold demonstrated high stability in the course of prolonged electric cycling. It was shown that preliminary electrical stimulation facilitated proliferative activity of human dermal fibroblasts in comparison to that of intact cells. Keywords: chitosan/carbon nanotube composite, electrical stimulation, dermal fibroblasts.
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