Multiscale structures based on nanomaterials for the development of passive and active implantable devices that stimulate nerve tissue
Murashko D.T.1, Efremova K.D.2, Putrya B.M.1, Eganova E.M.3, Gerasimenko A.Yu.1,2
1Institute of Biomedical Systems, National Research University MIET, Moscow, Zelenograd, Russia
2Institute for Bionic Technologies and Engineering, Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russia
3Institute of Nanotechnology of Microelectronics of the Russian Academy of Sciences, Moscow, Russia
Email: skorden@outlook.com
This study presents the creation of multiscale structures based on nanomaterials for the fabrication of passive and active implantable devices that stimulate neural tissue through the use of laser microstructuring and carbon nanotube coatings. Results of surface morphology studies revealed the formation of a distinctly ordered surface with protruding vertical arrays and depressions. The greatest height of the arrays, in the range of 55-72 μm, was achieved in the sample irradiated with a laser power of 5.7 W. Scanning electron microscopy also confirmed the formation of a uniform coating of single-walled carbon nanotubes. Energy-dispersive X-ray spectroscopy confirmed the expected increase in oxide phases when laser radiation was used in air. At the same time, the application of a nanotube coating led to the expected increase in carbon content on the sample surfaces. A study was conducted on the effect of laser irradiation and nanotube coating on the electrical conductivity of the samples. During cyclic voltammetry, the expected response was obtained, showing that the control sample exhibited no catalytic activity compared to the other samples. The sample irradiated with 4 W laser radiation and coated with single-walled nanotubes exhibited the highest combination of cycle stability (98.7 %) and areal capacitance 125.7 μF/cm2. Keywords: carbon nanotubes, medical-grade steel, laser radiation, multiscale structures, neurostimulation.
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