Interaction of laser radiation with avascular biological tissues depending on their thickness and absorption changes
Kasianenko E. M.1, Yuzhakov A.V. 1, Baum O. I. 1
1National Research Center “Kurchatov Institute”, Moscow, Russia
Email: baumolga1@mail.ru

PDF
This article examines the interaction of near-IR laser radiation at wavelengths of 1.56 μm and 1.45 μm with avascular biological tissues of varying thicknesses, with absorption changing due to the diffusion of a clearing agent glycerol in varying percentages. The sample thicknesses are correlated with the thickness of various avascular biological tissues in the body: the range studied ranges from "thin"; samples simulating the tympanic membrane to "thick"; samples corresponding to articular and costal cartilage. A sample thickness of 500 μm represents the "borderline"; thickness, relative to which the transmitted intensity dynamics vary for two wavelengths 1.56 μm and 1.45 μm. The obtained results indicate the possibility of controlling the thermal effect by selecting the wavelength and concentration of the active clearing agent, which is essential when determining the therapeutic ranges of laser exposure parameters for biological tissue. Keywords: laser, avascular biotissue, cartilage, tympanic membrane, glycerol.
  1. Y.M. Alexandrovskaya, O.I. Baum, A.V. Yuzhakov, V.M. Svistushkin, A.V. Buzmakov, Yu.S. Krivonosov, B.S. Roshchin, D.A. Zolotov. Lasers Surg. Med., 53 (2), 275--283 (2021). DOI: 10.1002/lsm.23266
  2. V.Y. Zaitsev, A.L. Matveyev, L.A. Matveev, G.V. Gelikonov, D.V. Shabanov, A.A. Sovetsky, A.I. Omelchenko, O.I. Baum, A. Vitkin, E.N. Sobol. Proc. SPIE, 10496, 104960--104965 (2018). DOI: 10.1117/12.2289777
  3. E.N. Sobol, O.I. Baum, A.B. Shekhter, A.V. Guller. J. Biomed. Opt., 22 (9), 091515 (2017). DOI: 10.1117/1.JBO.22.9.091515
  4. O.I. Baum, Yu.M. Soshnikova, A.I. Omelchenko, E.N. Sobol. Proc. SPIE, 8595, 85951K (2013). DOI: 10.1117/12.2008536
  5. E.N. Sobol, A.B. Shekhter, A.V. Guller, O.I. Baum, A.V. Baskov. J. Biomed. Opt., 16 (8), 080902 (2011)
  6. Yu.M. Alexandrovskaya, O.I. Baum, A.B. Shekhter, E.V. Petersen, O.A. Tiflova, A.K. Dmitriev, V.A. Ulyanov, V.M. Svistushkin, L.V. Selezneva, E.N. Sobol. Laser Phys. Lett., 15, 085601 (2018). DOI: 10.1088/1612-202X/aac746
  7. Yu.M. Soshnikova, O.I. Baum, E.M. Shcherbakov, A.I. Omelchenko, A.B. Shekhter, V.V. Lunin, E.N. Sobol. Lasers Surg. Med., 47 (3), 243--251 (2015)
  8. E.N. Sobol, N.N. Vorobieva, O.I. Baum, A.B. Shekhter, A.V. Guller. Lasers Surg. Med., 43 (S23), 911 (2011)
  9. K.F. Palmer, D. Williams. J. Opt. Soc. Am., 64 (8), 1107--1110 (1974)
  10. V.N. Bagratashvili, E.N. Sobol, A.B. Shekhter (eds.). Laser Engineering of Cartilage (Fizmatlit, Moscow, 2006), 486 p
  11. V.V. Tuchin, D. Zhu, E.A. Genina (eds.). Handbook of Tissue Optical Clearing: New Prospects in Optical Imaging (CRC Press, Boca Raton, 2022)
  12. E.A. Genina, A.N. Bashkatov, Yu.P. Sinichkin, I.Y. Yanina, V.V. Tuchin. J. Biomed. Photonics Eng., 1 (1), 22--58 (2015)
  13. V.D. Genin, D.K. Tuchina, A.J. Sadeq, E.A. Genina, V.V. Tuchin, A.N. Bashkatov. J. Biomed. Photonics Eng., 2 (1), 010303 (2016)
  14. H.A. MacKenzie, H.S. Ashton, S. Spiers, Y. Shen, S.S. Freeborn, J. Hannigan, P. Rae. Clin. Chem., 45 (9), 1587-1595 (1999)
  15. G.B. Christison, H.A. MacKenzie. Med. Biol. Eng. Comput., 31, 284--290 (1993)
  16. J.M. Hirshburg, K.M. Ravikumar, J.H. Hwang, A.T. Yeh. J. Biomed. Opt., 15 (5), 055002 (2010)
  17. K.V. Berezin, M.K. Berezin, S.A. Likhachev, N.Y. Shilyagina, K.N. Dvoretskiy. J. Mol. Model., 24 (2), 45 (2018)
  18. V.D. Genin, S.N. Churbanov, V.V. Dremin, V.V. Sidorov, E.V. Potapova, A.V. Dunaev, I.V. Meglinski. J. Innov. Opt. Health Sci., 14 (5), 2142006 (2021)
  19. T. Zahnert, K.B. Huttenbrink, D. Murbe, M. Bornitz. Audiol. Neurootol. (2000)
  20. A.A. Aarnisalo, J.T. Cheng, M.E. Ravicz, J.J. Rosowski. Otol. Neurotol. (2009)
  21. C.F. Lee, L.P. Hsu, P.R. Chen, Y.F. Chou, J.H. Chen, T.C. Liu. Audiol. Neurootol., 11 (6), 380--388 (2006)
  22. C.F. Lee, J.H. Chen, Y.F. Chou, L.P. Hsu, P.R. Chen, T.C. Liu. Laryngoscope, 117 (4), 725--730 (2007)
  23. D. Murbe, T. Zahnert, M. Bornitz, K.B. Huttenbrink. Laryngoscope, 112 (10), 1769--1776 (2002)
  24. T. Yang, X. Wu, X. Peng, Y. Zhang, S. Xie, H. Sun. Acta Otolaryngol., 136 (11), 1085--1090 (2016). DOI: 10.1080/00016489.2016.1195013
  25. W. Abdelhameed, I. Rezk, A. Awad. Braz. J. Otorhinolaryngol., 83 (5), 507--511 (2017). DOI: 10.1016/j.bjorl.2016.06.005
  26. S. Vadiya, S. Bhatt. Indian J. Otolaryngol. Head Neck Surg., 68 (1), 30--33 (2016). DOI: 10.1007/s12070-015-0830-y
  27. V.V. Tuchin. J. Biomed. Photonics Eng., 1, 98--134 (2015)
  28. E.A. Susaki, H.R. Ueda. Cell Chem. Biol., 23, 137--157 (2016)
  29. S. Johnsen, E.A. Widder. J. Theor. Biol., 199, 181--198 (1999)
  30. Y.M. Alexandrovskaya, O.I. Baum, A.B. Shekhter, E.N. Sobol. J. Biophotonics, 11 (2), e201700105 (2018)
  31. Physical Properties of Glycerine and Its Solutions (Glycerine Producers' Association, N.Y., 1963), p. 14
  32. Y. Muramatsu, A. Tagawa, T. Kasai. Food Sci. Technol. Res., 11 (3), 288 (2005)
Publisher:

Ioffe Institute

Institute Officers:

Director: Sergei V. Ivanov

Contact us:

26 Polytekhnicheskaya, Saint Petersburg 194021, Russian Federation
Fax: +7 (812) 297 1017
Phone: +7 (812) 297 2245
E-mail: post@mail.ioffe.ru