Volumes and Issues
Home » Optics and Spectroscopy » Year 2025, issue 12 » Article p. 1218
<<<>>>
Estimation of two-layered media extinction by sapphire fiber probe and diffuse reflectance analysis
Russian version
Platonova A. A. 1, Zotov A. K. 1, Kochiev D. G. 1, Zaytsev K. I. 1, Kurlov V. N. 2, Dolganova I. N. 1,2
1Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia
2Osipyan Institute of Solid State Physics RAS, Chernogolovka, Russia
Email: platlina.hibou2001@yandex.ru, in.dolganova@gmail.com
PDF
Measuring the optical parameters of biological tissues using diffuse reflectance methods is widely used for non-invasive monitoring of various conditions. One particular application is the analysis of the parameters of various volumetric inclusions and tissue layers. For this purpose, this paper examines a sapphire fiber probe that measures an effective extinction coefficient of biological tissue using analysis of spatially resolved diffuse reflectance. It is based on four-channel laser illumination of the object under study and the analysis of diffuse reflected intensity in steady-state mode. To evaluate the probe's sensitivity to inclusions, two-layer polyacrylamide-based phantoms with varying top-layer thicknesses were developed. A lipid emulsion of varying concentrations was used as the scattering component, creating a contrast in scattering properties at the interface between the phantom layers. As a result of experimental studies, it was shown that the measured effective extinction coefficient of such phantoms depends on the thickness of the top layer, and the probe allows estimation of heterogeneity or inclusions. Keywords: diffuse reflectance, effective extinction coefficient, sapphire, tissue phantom.
  1. C.A. denUil, E. Klijn, W.K. Lagrand, J.J. Brugts, C. Ince, P.E. Spronk, M.L. Simoons. Prog. Cardiovasc. Dis., 51 (2), 161--170 (2008). DOI: 10.1016/j.pcad.2008.07.002
  2. P.F. Do Amaral Tafner, F.K. Chen, R.R. Filho, T.D. Corr\^ea, R.C. De Freitas Chaves, A.S. Neto. Rev. Bras. Ter. Intensiva., 29 (2), 238--247 (2017). DOI: 10.5935/0103-507X.20170033
  3. R. Fitridge, M. Thompson. Mechanisms of vascular disease: A reference book for vascular specialists (The University of Adelaide Press, Adelaide, 2011). DOI: 10.1017/UPO9781922064004
  4. N. Nakayama, S. Kuroda, K. Houkin, S. Takikawa, H. Abe. Acta. Neurochir., 143 (1), 17--24 (2001). DOI: 10.1007/s007010170133
  5. A.V. Pushkarev, S.S. Ryabikin, D.I. Tsiganov, A.K. Zotov, V.N. Kurlov, I.N. Dolganova. J. Biomed. Photon. Eng., 8 (4), 040501 (2022). DOI: 10.18287/JBPE22.08.040501
  6. I.N. Dolganova, A.K. Zotov, L.P. Safonova, P.V. Aleksandrova, I.V. Reshetov, K.I. Zaytsev, V.V. Tuchin, V.N. Kurlov. J. Biophotonics, 16 (3), e202200288 (2023). DOI: 10.1002/jbio.202200288
  7. C. Holm., M. Mayr, E. Hofter, A. Becker, U.J. Pfeiffer, W. Muhlbauer. Br. J. Plast. Surg., 55 (8), 635--644 (2002). DOI: 10.1054/bjps.2002.3969
  8. D.K. Tuchina, V.V. Tuchin. J. Biomed. Photon. Eng., 4 (2), 020201 (2018). DOI: 10.18287/jbpe18.04.020201
  9. E. Zharkikh, V. Dremin, E. Zherebtsov, I. Meglinski. J. Biophotonics, 13 (10), 202000203 (2020). DOI: 10.1002/jbio.202000203
  10. V.V. Tuchin. Tissue optics: Light scattering methods and instruments for medical diagnosis (SPIE, California, 2015). DOI: 10.1117/3.1003040
  11. M.G. Nichols, E.L. Hull, T.H. Foster. Appl. Opt., 36 (1), 93--104 (1997). DOI: 10.1364/AO.36.000093
  12. Z. Shi, Y. Fan, H. Zhao, K. Xu. J. Biomed. Opt., 17 (6), 067004 (2012). DOI: 10.1117/1.jbo.17.6.06700
  13. A.M.K. Nilsson, R. Berg, S. Andersson-Engels. Appl. Opt., 34 (21), 4609--4619 (1995). DOI: 10.1364/ao.34.004609
  14. B. Hallacoglu, A. Sassaroli, S. Fantini. PLoS One, 8 (5), e64095 (2013). DOI: 10.1371/journal.pone.0064095
  15. A.K. Zotov, A.V. Pushkarev, A.I. Alekseeva, K.I. Zaytsev, S.S. Ryabikin, D.I. Tsiganov, D.A. Zhidkov, I.A. Burkov, V.N. Kurlov, I.N. Dolganova. Sensors, 24 (11), 3655 (2024). DOI: 10.3390/s24113655
  16. A.A. Platonova, P.V. Alexandrov, S.P. Kudryavtseva, A.K. Zotov, K.I. Zaitsev, K.B. Dolganov, V.N. Kurlov, I.N. Dolganova. Opt. i spektr., 133 (5), 473--479 (2025) (in Russian). DOI: 10.61011/OS.2025.05.60784.201-24
  17. A.A. Platonova, P.V. Aleksandrova, A.I. Alekseeva, S.P. Kudryavtseva, A.K. Zotov, K.I. Zaytsev, K.B. Dolganov, I.V. Reshetov, V.N. Kurlov, I.N. Dolganova. J. Biophotonics, 17 (11), e202400368 (2024). DOI: 10.1002/jbio.202400368
  18. K. Stock, T. Stegmayer, R. Graser, W. Forster, R. Hibst. Las. Surg. Med., 44 (10), 815--823 (2012). DOI: 10.1002/lsm.22091
  19. I.N. Dolganova, I.A. Shikunova, A.K. Zotov, M.A. Shchedrina, I.V. Reshetov, K.I. Zaytsev, V.V. Tuchin, V.N. Kurlov. J. Biophotonics, 13 (10), e202000164 (2020). DOI: 10.1002/jbio.202000164
  20. M. Ahmad, M. Ismail. J. Cosmet. Dermatol., 20 (11), 3610--3615 (2021). DOI: 10.1111/jocd.14006
  21. T.J. Polletto, A.K. Ngo, A. Tchapyjnikov, K. Levin, D. Tran, N.M. Fried. Las. Surg. Med., 38 (8), 787--791 (2006). DOI: 10.1002/lsm.20382
  22. H.E. LaBelle. J. Cryst. Growth, 50 (1), 8--17 (1980). DOI: 10.1016/0022-0248(80)90226-2
  23. V.N. Kurlov, S.N. Rossolenko, N.V. Abrosimov, K. Lebbou. Crystal Growth Processes Based on Capillarity: Czochralski, Floating Zone, Shaping and Crucible Techniques (John Wiley and Sons, Capstone, 2010). Ch. 5. DOI: 10.1002/9781444320237
  24. T.J. Farrell, M.S. Patterson, B. Wilson. Med. Phys., 19 (4), 879--888 (1992). DOI: 10.1118/1.596777
  25. A. Liemert, A. Kienle. Opt. Expr., 18 (9), 9266--9279 (2010). DOI: 10.1364/OE.18.009266
  26. H. Assadi, R. Karshafian, A. Douplik. Int. J. Photoenergy, 2014 (1), 471764 (2014). DOI: 10.1155/2014/471764
  27. S.T. Flock, S.L. Jacques, B.C. Wilson, W.M. Star, M.J. van Gemert. Las. Surg. Med., 12 (5), 510--519 (1992). DOI: 10.1002/lsm.1900120510
  28. S.R. Guntur, M.J. Choi. Ultrasound Med. Biol., 40 (11), 2680--2691 (2014). DOI: 10.1016/j.ultrasmedbio.2014.06.010
  29. A. Hariri, J. Palma-Chavez, K.A. Wear, T.J. Pfefer, J.V. Jokerst, W.C. Vogt. Photoacoustics, 22 (22), 100245 (2021). DOI: 10.1016/j.pacs.2021.100245
  30. B. Aernouts, R. Van Beers, R. Watte, J. Lammertyn, W. Saeys. Opt. Expr., 22 (5), 6086--6098 (2014). DOI: 10.1364/oe.22.006086
Publisher:

Ioffe Institute

Institute Officers:

Director: Sergei V. Ivanov

Contact us:

26 Polytekhnicheskaya, Saint Petersburg 194021, Russian Federation
Fax: +7 (812) 297 1017
Phone: +7 (812) 297 2245
E-mail: post@mail.ioffe.ru