Spectro-luminescent research of 1-pyrenemethylamine interaction with nucleic acids in water
Malkova U. A.
1, Demidov E. V.
1, Kuzmina N. V.
2, Plekhanov A. Yu.
3, Puzyk M. V.
11Herzen State Pedagogical University of Russia, St. Petersburg, Russia
2St. Petersburg State Pediatric Medical University, St. Petersburg, Russia
3 Smorodintsev Research Institute of Influenza (a Russian Ministry of Health federal institution), St. Petersburg, Russia
Email: puzyk@mail.ru
The interactions of 1-pyrenemethylamine hydrochloride with nucleic acids (calf thymus DNA and yeast RNA) in water were studied using electron absorption and emission spectroscopy. The totality of the obtained spectral data allows us to conclude that 1-pyrenemethylamine is intercalated in DNA but not in RNA. Keywords: intercalation, 1-pyrenemethylamine, calf thymus DNA, yeast RNA.
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