Application of high-resolution terahertz spectroscopy to study the chemical composition of thermal decomposition products of bladder cancer tissues
Vaks V.L.
1,2, Anfertev V.A.
1, Domracheva E.G.
1,2, Chernyaeva M.B.
1,2, Atduev V.A.
3,4, Atduev K.A.
3, Cherniaeva A.S.
11IPM RAS, Nizhny Novgorod, Russia
2Lobachevsky State University, Nizhny Novgorod, Russia
3Privolzhsky District Medical Center of the Federal Medical and Biological Agency of Russia, Nizhny Novgorod, Russia
4Privolzhsky Research Medical University, Nizhny Novgorod, Russia
Email: elena@ipm.sci-nnov.ru, anfertev@ipmras.ru, elena@ipmras.ru, masha@ipm.sci-nnov.ru, atduev@mail.ru, atduev7777@gmail.com, aleksacherny@gmail.com
Due to the need to detect oncological diseases at an earlier stage, when timely surgical or therapeutic treatment increases the likelihood of patient survival, it is urgent to search for and develop effective diagnostic and therapeutic strategies. Approaches based on metabolomics have the potential to identify sets of metabolite markers of cancer, which is important for early cancer recognition. One of the types of cancer that are difficult to detect in the early stages in modern conditions is urothelial cancer, for which the metabolic approach is promising in the early stages. The work is devoted to the study of the chemical composition of thermal decomposition products of primary metabolites for bladder tumor tissues, conducted for the first time using high-resolution THz spectroscopy methods. Keywords: bladder cancer, biological tissue, thermal decomposition products, metabolites, high-resolution THz spectroscopy.
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