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Features of infrared spectra of blood serum of patients with multiple myeloma
Russian version
DOI: 10.61011/EOS.2023.06.56663.105-23
Chernyshev D. A.1, Mikhailets E. S.1, Plotnikova L. V.1, Garifullin A. D.1,2, Kuvshinov A. I.2, Voloshin S. V.2,3, Polyanichko A. M. 1,4
1St. Petersburg State University, St. Petersburg, Russia
2Russian Research Institute of Hematology and Transfusiology, Saint-Petersburg, Russia
3Kirov Military Medical Academy, St. Petersburg, Russia
4Institute of Cytology Russian Academy of Science, Saint-Petersburg, Russia
Email: lfybbk1399123@gmail.com, elinamikhailets@mail.ru, a.polyanichko@spbu.ru
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A comparative analysis of infrared (IR) spectra of blood serum of healthy donors and patients with multiple myeloma (MM) is carried out. The MM is characterized by hyperproduction of paraprotein, which manifests in a change in the IR absorption spectrum profile in the mid-IR range. It is shown the most significant deviations in spectra are observed for the samples of secretory MM near Amide I and Amide II' bands. As a result of the comparative analysis of IR spectra of blood serum in the region of 1700-1350 cm-1 9 parameters were identified, which average values in samples taken from patients with secretory MM form are significantly different from the same parameters of healthy donor serum. Keywords: IR spectroscopy, multiple myeloma, blood serum, secondary structure of proteins. DOI: 10.61011/EOS.2023.06.56663.105-23
  1. S.V. Rajkumar. Am. J. Hematol., 95, 548-567 (2020). DOI: 10.1002/ajh.25791
  2. B. Sirohi, R. Powles. Eur. J. Canc., 4 (11), 1671-1683 (2006). DOI: 10.1016/j.ejca.2006.01.065
  3. K.C. Nau, W.D. Lewis. Am. Farm. Physician., 78 (7), 853-859 (2008)
  4. R.L. Siegel, K.D. Miller, A. Jemal. Cancer J. Clinic., 66 (1), 7-30 (2016). DOI: 10.3322/caac.21332
  5. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, M.J. Thun. Cancer J. Clinic., 59 (4), 225-249 (2009). DOI: 10.3322/caac.20006
  6. R.L. Siegel, K.D. Miller, A. Jemal. Cancer J. Clinic., 70 (1), 7-30 (2020). DOI: 10.3322/caac.21590
  7. S.V. Rajkumar, S. Kumar. Mayo Clinic Proceedings., 91 (1), 101-119 (2016). DOI: 10.1016/j.mayocp.2015.11.007
  8. R.A. Kyle, S.V. Rajkumar. New Engl. J. Med., 351 (18), 1860-1873 (2004). DOI: 10.1056/NEJMra041875
  9. D.D. Alexander, P.J. Mink, H.O. Adami, P. Cole, J.S. Mandel, M.M. Oken, D. Trichopoulos. Int. J. Canc., 120 (12), 40-61 (2007). DOI: 10.1002/ijc.22718
  10. A. Palumbo, K. Anderson. New Engl. J. Med., 364 (11), 1046-1060 (2011). DOI: 10.1056/NEJMra1011442
  11. Dupuis MM, Tuchman SA. Onco Targets Ther., 9, 7583-7590 (2016). DOI: 10.2147/OTT.S122241
  12. S.V. Rajkumar, M.A. Dimopoulos, A. Palumbo et al. Lancet Oncol., 15 (12), 538-548 (2014). DOI: 10.1016/S1470-2045(14)70442-5
  13. A. Smith, F. Wisloff, D. Samson. Brit. J. Haematol., 132 (4), 410-451 (2006). DOI: 10.1111/j.1365-2141.2005.05867.x
  14. M. Dimopoulos, R. Kyle, J.P. Fermand, S.V. Rajkumar, J. San Miguel, A. Chanan-Khan. Blood, 117 (18), 4701-4705 (2011). DOI: 10.1182/blood-2010-10-299529
  15. L. Benezzeddine-Boussaidi, G. Cazorla, A.M. Melin. Clinic. Chem. Lab. Med., 47 (1), 83-90 (2009). DOI: 10.1515/CCLM.2009.007
  16. V.E. Sitnikova, M.A. Kotkova, T.N. Nosenko, T.N. Kotkova, D.M. Martynova, M.V. Uspenskaya. Talanta, 214, 120857 (2020). DOI: 10.1016/j.talanta.2020.120857
  17. J. Titus, H. Ghimire, E. Viennois, D. Merlin, A.G. Unil Perera. J. Biophoton., 11 (3), (2017) DOI: 10.1002/jbio.201700057
  18. E.A. Telnaya, L.V. Plotnikova, A.D. Garifullin, A.Yu. Kuvshinov, S.V. Voloshin, A.M. Polyanichko. Biophysics, 65 (6), 981-986 (2020). DOI: 10.1134/S0006350920060214
  19. S. Hu, J.A. Loo, D.T. Wong. Proteomics., 6 (23), 6326-6353 (2006). DOI: 10.1002/pmic.200600284
  20. L.V. Plotnikova, M.O. Kobeleva, E.V. Borisov, A.D. Garifullin, A.V. Povolotskaya, S.V. Voloshin, A.M. Polyanichko. Cell and Tissue Biology, 13 (2), 130-135 (2019). DOI: 10.1134/S1990519X19020093
  21. A.M. Polyanichko, V.V. Andrushchenko, E.V. Chikhirzhina, V.I. Vorob'ev, H. Wieser. Nucleic Acids Res., 32 (3), 989-996 (2004). DOI:10.1093/nar/gkh242
  22. J.R. Powell, F.M. Wasacz, R.J. Jakobsen. Appl. Spectrosc., 40 (3), 339-344 (1986)
  23. A.M. Polyanichko, N.M. Romanov, T.Y. Starkova, E.I. Kostyleva, E.V. Chikhirzhina. Cell and Tissue Biology, 8 (4), 352-358 (2014). DOI: 10.1134/S1990519X14040087
  24. M. Baldassarre, A. Scire, F. Tanfani. Biomed. Spectrosc. Imag., 1 (3), 247-259 (2012). DOI: 10.3233/bsi-2012-0021
  25. Y.N. Chirgadze, O.V. Fedorov, N.P. Trushina. Biopolymers, 14 (4), 679-694 (1975). DOI: 10.1002/bip.1975.360140402
  26. K. Rahmelow, W. Hubner, T. Ackermann. Analyt. Biochem., 257 (1), 1-11 (1998). DOI: 10.1006/abio.1997.2502
  27. A. Barth. Biochim. Biophys. Acta, 1767 (9), 1073-1101 (2007). DOI: 10.1016/j.bbabio.2007.06.004
  28. L.V. Plotnikova, M.O. Kobeleva, E.V. Borisov, A.D. Garifullin, A.V. Povolotskaya, S.V. Voloshin, A.M. Polyanichko. Cell and Tissue Biology, 13 (2), P. 130-135 (2019). DOI: 10.1134/S1990519X19020093
  29. J. Depciuch, M. Sowa-Kucma, G. Nowak, M. Papp, P. Gruca, P. Misztak, M.Parlinska-Wojtan. Spectrochim. Acta A, 176, 30-37 (2017). DOI: 10.1016/j.saa.2016.12.007

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